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August 2005 issue

The Drug Days of Summer - Biggest Deals, Most Dollars in Health Care M&A Tied to Pharmaceuticals
Two of the biggest names in generic pharmaceuticals come together in one of the largest deals of the year, and several smaller deals get done.
...
Seedling Firm, Seasoned Team - Venture Capital Spin-Off With Plenty of Funding Planted In Health Care
Venture capitalists continue to plow money into health care, with a handful of deals involving one firm that is now restructuring.
...
Public Equity Market
Just one health care IPO got priced in the past two weeks, but it was a real doozy; two secondaries got priced, and there were no withdrawals.
...
Private Equity Market
The flow of private equity that was flooding the health care markets in our last issue has slowed, but the current is still moving along.
...
To Better Days
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Companies Mentioned in this issue: August 2005
A
Accentia p3
Adams Respiratory Therapeutics p3
Adherex Technologies p4
Advanced Life Scien. p3
Advanced Life Sciences p3
Advantage Capital Alabama p7
ADVENTRX Pharmaceuticals p3, p4
Affymax p1
Alliance Medical Corporation p7
Apax Partners p3
ART Advanced Research p4
Aspreva Pharmaceuticals p7
B
Banc of Am p3
C
C.E. Unterberg, Tow p3
CareerBuilder.com p8
CIBC World Markets p4
Cornell Capital Partners p3
Cornell Capital Partners, LP. p4
Credit Suisse First Boston p1
CSFB p3
CuraScript p2
Cytogen Corporation p4
D
Deutsche Bank p3
E
Express Scripts, Inc. p2
G
GEN3 Capital p7
GTCR Golder Rauner p2
H
Healthcare Acquisit. p3
HospiScript Services p7
I
Ilypsa p1
Introgen Therapeutics p3
IVAX Corporation p2
J
Jefferies p3
Jefferies & Company p4
L
Labcyte p1
Leerink Swann p4
LifeCare Holdings p2
M
MDB Capital Group LLC p4
Merrill p3
Merrill Lynch p3
Momenta Pharmaceu. p3
Morgan p3
Morgan Keegan p7
Morgan Stanley p3
MPM Capital p7
Mulier Capital Limited p4
N
National Bureau of Economic Research p8
New Enterprise Associates p7
New Leaf Venture Partners p1
New York University p8
NLV Partners p1
NxStage Medical p1, p3
P
Peptimmune p7
Pharmacopeia p4
Priority Healthcare Corporation p2
R
Raymedica p7
RBC Capital Markets p4
Remedent p4
S
Saint Louis University of Medicine p8
Select Medical Corporation p2
SemperCare p2
Spherix p4
Spherix Incorporated p3
Spine Solutions p7
Sprout Group p1
SR Pharma p3, p4
SurgRx p7
Symmetry Medical p3
T
Teva Pharmaceuticals p2
The Carlyle Group p2
The Immune Response Corporation p3, p4
U
U.S. House of Representatives p8
V
Vasomedical p4
Versant Partners p4
Viscogliosi & Company p7
Viscogliosi Brothers p7
W
Waveland NCP Alabama Ventures p7
WebMD Corporation p7
Wharton Capital Partners p4
Winchester Capital p4
Z
ZymoGenetics p3

The Drug Days of Summer - Biggest Deals, Most Dollars in Health Care M&A Tied to Pharmaceuticals

Pharmaceutical manufacturers, developers and the companies that serve them continued to dominate the health care merger and acquisition market during the second half of July. Pharmaceuticals and pharmaceuticals-related companies accounted for nearly 85% of all capital committed to health care M&A in those two weeks. The combined dollar total of the five Pharmaceutical sector acquisitions, plus the one deal in which a pharma is acquiring a biotech and the three deals involving companies that service the industry is $10.5 billion.

In all the health care sectors, a total of nearly $12.4 billion was committed to finance 20 mergers and acquisitions during the two weeks ended July 31, 2005, based on deals with revealed prices. Even strictly speaking, the Pharmaceutical sector accounted for 73% of the dollar total—plus the single largest deal, and the second largest number of deals announced in one sector for those two weeks. Companies classified as Other posted more health care mergers and acquisitions than any other single sector, including the second largest deal, which involved a pharmacy benefit manager and a specialty pharma.

In the most impressive transaction of the past two weeks, Teva Pharmaceuticals (NASDAQ: TEVA) is acquiring IVAX Corporation (AMEX: IVX) for nearly $8 billion, including assumed debt. Each common share of IVAX’s stock may be converted into $26.00 cash or 0.8471 shares of TEVA’s American Depository Receipts, at the option of the holders. This transaction unites the two generic pharmaceutical companies with a triangular merger structure that causes IVAX to become a subsidiary of TEVA, effectively creating the largest generic drug company we know of in the industry. The resulting entity will operate directly in over 50 countries and is expected to generate sales of over $7 billion, offering a wide range of generic and branded pharmaceuticals to consumers, customers and health care providers.

In the only other deal to pass the billion-dollar mark during the past two weeks, Express Scripts, Inc. is acquiring Priority Healthcare Corporation (NASDAQ: PHCC) for $1.3 billion in cash, or $28.00 per share. The resulting entity is combining Priority Healthcare with Express Scripts’ specialty pharmaceuticals unit, CuraScript, which will now be one of the largest specialty pharmacy and distribution companies in the United States, and is expected to generate more than $3 billion in annual revenues.

CuraScript offers a spectrum of specialty injectable medications to individuals with chronic illnesses, and combined with the assets of Priority Healthcare, the company now provides biopharmaceuticals and complex therapies, plus related disease treatment programs and services, to patients, payors, physicians and pharmaceutical manufacturers. Treatment areas include endocrinology, gastroenterology, hematology, infectious disease, nephrology, neurology, oncology, ophthalmology, pulmonology, reproductive endocrinology and rheumatology.

The third-largest deal of the month is rather unusual, with The Carlyle Group acquiring a portfolio of Long Term Acute Care hospitals (LTACs) for approximately $555 million. Deals so rarely get done in this subsector that the most recent, most comparable transaction was announced late last year, when Select Medical Corporation purchased SemperCare, which operated 17 LTACs in nine states with $147.5 million of revenue, for $100 million, or 0.68x revenues.

The Carlyle Group is purchasing 21 LTACs with more than 1,000 beds in nine states, collectively known as LifeCare Holdings, from GTCR Golder Rauner LLC for more than $550,000 per bed. LifeCare’s revenues for the 12 months ended March 31, 2005 were about $335 million, and based on industry margins, we assume that EBITDA for that period would be close to $75 million, yielding a cash flow multiple of 7.4x.

LifeCare Holdings is the third-largest LTAC provider in the United States, with facilities in Colorado, Michigan, Pennsylvania, Ohio and five other states. Interestingly, less than 50% of LifeCare’s LTACs are freestanding, which means that most of the purchase price is related to the LTAC business, and not any associated real estate. The health care group, and not the real estate group, of Carlyle made this investment. Although the LifeCare deal implies a huge per-bed value for the entire enterprise, it doesn’t look like Carlyle was buying it for the real estate, especially since very little real estate seems to have been part of that deal.

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Since 1948, Irving Levin Associates, Inc. has been the leading source of information and investment research on mergers and acquisitions in the Behavioral Health Care, Biotech, e-Health, Home Health Care, Hospitals, Laboratories, MRI and Dialysis, Long Term Care, Managed Care, Medical Devices, Pharmaceuticals, Physician Medical Groups, Rehabilitation and other health care markets.

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