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In the July 2005 issue:

UnitedHealth Group Offers $9.2 Billion to Buy PacifiCare
Size does seem to matter, as UnitedHealth crafts a $9.2 billion deal to buy PacifiCare and become the country’s largest MCO.
...
Consolidation Spikes in the Generic Pharmaceuticals Market
Consolidation among generic pharma companies is increasing in response to the opportunities created as brand-name drugs lose their exclusivity.
...
Second Quarter Results
A total of 211 mergers and acquisitions were announced in the second quarter of 2005. $18.4 billion was committed to fund this M&A activity.
...
In The Departments
The Month in Deals
Service Sectors
Service Summaries
Additional Transactions
Transaction Updates
Technology Sectors
Technology Summaries

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Companies mentioned in this issue:

A
aaiPharma p13
ABN AMRO p10
Adventist Health System—Sunbelt p4
Aerojet Fine Chemicals p13
Aetna p4
AIG Global Investment Group p13
Alkermes p13
Allied Capital Corporation p7
Amedisys p4
American Pacific Corp. p13
Anthem p3
Apax Partners p13
B
Balanced Care Corp. p9
Banc of America Securities p13
Bank Degroof p10
Bausch and Lomb p13
Bay Area Mobile Apheresis Program p8
BayNorth Capital p9
Bedford Community Medical Center p7
BiosPacific p11
Blue Chip Venture Company p13
Bradley Memorial Hospital p7
Bristol-Myers Squibb p10
Brookdale Living Communities p8
C
Callidus Capital Finance, LLC p11
Catholic Healthcare Partners p7
CB Richard Ellis p8
Celtic Pharma p11
Cephalon p13
CIVCO Medical Instruments Co. p12
Cleveland Community Hospital p7
Clinical Data p11
Coleman Swenson Hoffman Booth p13
Community Health Systems p7
D
D&K Healthcare Resources p10
Danaher Corp. p12
Deutsche Bank AG p8
Docupharma p10
Dr. Reddy’s Laboratories p10
Dun & Bradstreet p10
E
Eon Labs p10
EPI Corp. p8
Essex Woodlands p13
Evergreen Health Care p4
excellRx p9
F
Fischer Imaging Corp. p13
Fortress Investment Group p8
Fortron Bio Science p11
G
Geisinger Health System p7
Geisinger Wyoming Valley Medical Center p7
Genaissance Pharmaceuticals p11
GenCorp p13
GMAC Financial Services p8
H
HCA p7
Health Net p4
Healthcare Ventures p13
HealthSouth p8
Heumann Pharma GmbH & Co. Generica KG p10
Hexel AG p10
HMS Healthcare p9
Hologix p13
Housecall Medical Resources p4
I
IMS Health p10
InKine Pharmaceutical p13
IPC-AL REIT p9
J
Jubilant Organosys Ltd. p11
K
Kremer Laser Eye p10
L
Leiner Health Products p11
LifePoint Hospitals p7
M
Matrix Laboratories p10
McKesson Corp. p10
Medcon p11
Medical Properties Trust p9
Medimop Medical p12
Medtronic p12
Mercy Hospital p7
Merrill Lynch Capital p9
Morgan Stanley p4
MPM Capital p13
N
NeighborCare p9
Northern California Rehabilitation Hospital p9
Novartis p10
O
Omnicare p9
On-Call Plus p4
Oxford Health Plans p3
P
PacifiCare Health Systems p1
Pelton & Crane p12
Perseus-Soros BioPharmaceutical Fund p13
Pfizer p1
Pharmaceutical Formulations p11
Prudential Real Estate Investors p8
R
Reliant Pharmaceutical p11
Renal Care Group p8
ResCare p4
Roper Industries p12
Royal Philips Electronics p11
RxCrossroads, LLC p9
S
Salix Pharmaceuticals p13
Sandoz p10
Shandong Chia Tai Freda p13
Sicor p10
Silver Point Fund p13
Sino Biopharmaceutical p13
Spear Dermatology Products p11
Spear Pharmaceuticals p11
St. Rose Hospital p8
Stada Arzneimittel p10
Stentor p11
Strides Arcolab, Ltd. p10
T
TBMM Healthcare p9
Techne Corp. p11
Teva Pharmaceuticals p10
TLC Vision p10
Torrent Pharmaceuticals p10
Transneuronix p12
Triax Holdings, LLC p11
Trinity Laboratories p11
Tyco International Ltd. p12
U
UBS p10
UBS Securities LLC p13
United Rehab, LLC p8
UnitedHealth Group p1
V
Valleylab p12
Via Christi Health System p8
Vibra Healthcare p9
Vicuron Pharmaceuticals p1
Vivant Medical p12
VNU, NA p10
W
Wellchoice p4
WellPoint p1
West Pharmaceutical Services p12
X
Xanodyne Pharmaceuticals p13
Xenova Group plc p11


The Health Care M&A Monthly

Consolidation Spikes in the Generic Pharmaceuticals Market

Over the past few months, news in
the Pharmaceutical M&A market has focused on big pharma buying late-stage biotechs and other drug development companies to find the new blockbuster as their existing drugs go off patent and lose exclusivity. To cite but one example, last month we profiled Pfizer’s (NYSE: PFE) $1.9 billion acquisition of Vicuron Pharmaceuticals.

While the loss of exclusivity may be a worry for one company, it can also represent an opportunity for another. And this is where the generic market comes into play. It is true that some drugs are so tricky to manufacture that generic companies won’t pick them up after they go off patent. But, in general, the generic companies are not faced with the costs of paying for R&D, funding clinical trials or creating a new market for the drugs.

In theory—and in practice—this translates into the ability to manufacture and sell generic equivalents more cheaply than the brand-name drugs on which they are based. Also, with the help of managed care formularies, they can begin to capture market share from their costlier brand-name counterparts.

Generic pharmaceutical companies figured prominently among this month’s Pharmaceutical M&A market. This activity appears to be, in part, a response to Novartis’ (NYSE: NVS) $8.4 billion acquisition of Hexel AG and Eon Labs, announced in February. When consummated and combined with NVS’ generic Sandoz unit, this deal will create the world’s largest generic pharma business with annual revenue of $5 billion, displacing Teva Pharmaceuticals (NASDAQ: TEVA) from its number-one position.

Rumors swirled in the German and Israeli press during late June that Teva was angling to buy Stada Arzneimittel (DE: STAGn), Germany’s third-largest generic drug manufacturer, for €36 a share for a total of €2 billion ($2.4 billion). Based on Stada’s 2004 results, the price would be 2.46x revenue and 22.8x EBITDA. Such a deal would return Teva to the coveted top spot among generic pharma companies. However, coming a year after Teva’s $3.4 billion purchase of Sicor, the biggest acquisition in Israeli history, this could stretch Teva’s resources a bit thin.

And while those rumors continue to waft through the media, Novartis has taken positive steps to open up its lead by acquiring the U.S. and Canadian consumer medicines business of Bristol-Myers Squibb (NYSE: BMY) for $660 million in cash. Based on 2004 sales of these drugs in North America, the P/R multiple is 2.7x.

Interestingly, three of the generic deals this month originated in India. This spate of activity is due, in part, to the Government of India’s enactment of tougher patent protection laws in January. In addition to making India more attractive to foreign investors, a further consequence of these laws is that Indian drugmakers can no longer sell copycat drugs at home, so they are turning to overseas markets for products. In doing so, they hope to emulate the success of Dr. Reddy’s Laboratories (NYSE: RDY).

In the largest of the these three deals, Matrix Laboratories (BO: MAXL) is paying $263 million to buy a majority interest in Docupharma (BR: DOCH), a distributor of generic drugs in Belgium. Matrix is in the process of merging with Strides Arcolab, Ltd. to form India’s seventh-largest drug firm; this deal gives the company a base of operations in the heart of the European Union.

Taking into account the cash acquired in this deal, the net purchase price drops to $238 million, and the P/R multiple is 1.9x. UBS advised MAXL while ABN AMRO and Bank Degroof advised DOCH.

Torrent Pharmaceuticals (BO: TORP) is acquiring Heumann Pharma GmbH & Co. Generica KG, a German generic business, from Pfizer for an undisclosed price. The business being sold generates annual sales of about €50 million. International operations will account for 50% of the buyer’s revenue after the deal closes, up from 24% before.

Finally, Jubilant Organosys Ltd. (BO: 530019) is acquiring up to 75% of Trinity Laboratories, which manufactures generics in North Carolina, for as much as $24.7 million.

Within the United States, Pharmaceutical Formulations (OTCBB: PHFR), one of the four largest manufacturers of private-label products, is selling substantially all of its OTC solid-dose pharmaceuticals business to privately held Leiner Health Products for $23 million. Leiner is to purchase the assets through an auction process under section 363 of the bankruptcy code.

Triax Holdings, LLC, based in Mountain Lakes, New Jersey, is buying Spear Pharmaceuticals and Spear Dermatology Products, which market and distribute a generic equivalent of a leading topical acne medication, for approximately $133 million. Triax is headed by Joseph Krivulka, a well-known industry figure who was at the helm of Reliant Pharmaceutical until November 2004.

After cashing out its investment in Housecall Medical (see page 7), Allied Capital Corporation has invested $77 million in Triax to finance the Spear acquisitions. In connection with the deal, Triax also secured $56 million of senior debt financing through Callidus Capital Finance, LLC, which will syndicate a portion of the facility post-closing. Details about revenue and cash flow were not available.

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